Cis interactions of immunoreceptors with MHC and non-MHC ligands
نویسندگان
چکیده
منابع مشابه
Interactions of Ly49 family receptors with MHC class I ligands in trans and cis.
The Ly49A NK cell receptor interacts with MHC class I (MHC-I) molecules on target cells and negatively regulates NK cell-mediated target cell lysis. We have recently shown that the MHC-I ligand-binding capacity of the Ly49A NK cell receptor is controlled by the NK cells' own MHC-I. To see whether this property was unique to Ly49A, we have investigated the binding of soluble MHC-I multimers to t...
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ژورنال
عنوان ژورنال: Nature Reviews Immunology
سال: 2008
ISSN: 1474-1733,1474-1741
DOI: 10.1038/nri2278